Diklofen gel analogs:
Manufacturer Diklofen gel
active substance Diklofen gel
1.0 g of the gel contains 30 mg of diclofenac sodium and 5 mg of menthol.
Form of Diclofen-gel
Gel for 25 g in tubes.
Who can Diklofen gel
- therapy of rheumatoid arthritis,
- ankylosing spondylitis,
- acute gouty, infectious, psoriatic, and traumatic arthritis,
- osteoarthritis joints,
and other diseases accompanied by inflammation and pain syndrome.
Injuries to tendons, ligaments, muscles and joints( to relieve pain and inflammation during stretching, dislocations, bruises);localized forms of soft tissue rheumatism( to relieve pain and inflammation).
How to use Diclofen Gel
1.0 g of Diclofen Gel( 1 cm column of gel) is applied to the skin, to the affected joints or areas of the body where there is inflammation, easily rubbing for 1-2 minutes 2-4 times a day. The average daily dose is 4.0 g of gel, which corresponds to 120 mg of sodium diclofenac. For children older than 6 years and for adolescents, the daily dose should not exceed 2.0 g of the drug( 2 cm column of the gel), which must be divided 4 times. With the simultaneous use of Diclofen-gel and diclofenac sodium tablets, the daily dose of the latter should not exceed 50 mg.
The duration of the course of treatment is 10-14 days.
The drug should be applied only to intact skin areas, avoiding contact with eyes and mucous membranes. Be wary appoint patients who have a history of allergic reactions to non-steroidal anti-inflammatory drugs( NSAIDs), erosive and ulcerative diseases of the gastrointestinal tract, bronchial asthma, hematopoiesis. With prolonged use, periodic monitoring of the blood formula and liver function, analysis of feces for latent blood is necessary. Because of the possible reduction in the reaction rate, it is not recommended to drive vehicles and work with mechanisms that require an increased mental reaction. In the first 6 months of pregnancy, use is only possible on strict indications and in minimum effective doses. During lactation, the use of the drug requires the cessation of breast-feeding with mother's milk.
Side effects of Diclofen Gel
Diclofen-gel is usually well tolerated. Some patients with non-compliance with the rules of use or with an overdose may experience local irritation of the skin: itching, hyperemia, a feeling of heat, rashes, in some cases - the formation of an infiltrate, abscess, necrosis of adipose tissue. With long-term external application and / or when applied to extensive body surfaces, systemic side effects are possible due to the resorptive effect of diclofenac. There may be dizziness, headache, anxiety, insomnia, irritability, fatigue. Rarely - paresthesia, impaired vision, tinnitus, sleep disorder, convulsions, tremor, mental disorders, depression. Sometimes - anemia, leukopenia, thrombocytopenia, agranulocytosis.
To whom Diclofen-gel
is contraindicated Erosive-ulcerative gastrointestinal disturbances in the acute phase, triad caused by the action of acetylsalicylic acid - eosinophilic rhinitis, recurring pollinosis, hyperplastic sinusitis, impaired hematopoiesis of unclear etiology, hypersensitivity to diclofenac and gel components, other non-steroidal anti-inflammatory drugs. III trimester of pregnancy, children under 6 years.
Interaction of Diclofen-Gel
When using the drug in this dosage form, interaction with other drugs is not established. However, especially considering the possibility of simultaneous application of Diclofen-Gel and tablets of diclofenac sodium( the daily dose of the latter should not exceed 50 mg), it must be taken into account that the latter can potentiate specific effects and ulcerogenic effects of corticosteroids, increase the concentration of digoxin in the blood, weaken the actionthiazide diuretics and furosemide.
Combined use with potassium-sparing diuretics leads to hyperkalemia. Therapeutic efficacy with simultaneous use with salicylates is reduced, while ulcerogenic effect on the gastric mucosa is enhanced. When used simultaneously with anticoagulants, it is necessary to monitor the blood coagulation system.
Overdose of Diclofen Gel
When taking into account the method of administration and observing the dosage regimen, an overdose of Diclofen-Gel is unlikely. But when using the drug in high doses or when applied to a large area of the skin, the resorptive effect in the form of dizziness, headache, hyperventilation, confusion, myoclonic seizures in children, anorexia, nausea, vomiting, pain and discomfort in the epigastric region, bleedingfrom the digestive tract.
The onset of the above symptoms requires withdrawal of the drug or dose adjustment of Diclofen-Gel.
Treatment: remove or wash off the damaged area of the skin or joint gel that has remained. If necessary, conduct symptomatic therapy. Forced diuresis and hemodialysis are ineffective. There is no specific antidote.