Acyclovir Stud

Acyclovir Herds analogues:

Acyclovir Herds instruction:

Manufacturer:

Active ingredients Acyclovir Stud:

Form of production Acyclovir Stud:

  • Tablets of 200 mg No. 25, No. 100 in blisters.
  • Tablets of 400 mg No. 35 in blisters.
  • Tablets of 800 mg No. 35 in blisters.

Who is shown Acyclovir Stud?

Herpes simplex infections, genital herpes on the skin and mucous membranes( most often - recurrent genital herpes).

For the prevention of recurrence is shown to adults with complicated forms of frequent genital viral infections.

For the treatment of chickenpox and herpes zoster.

How to use Acyclovir Stud?

In the treatment of herpes simplex skin and mucous membranes, 200 mg are prescribed 5 times a day every 4 hours, except during the night sleep. The course of treatment - 5 days, if ne

cessary, can be extended. With severe immunodeficiency( including after bone marrow transplantation or intestinal absorption violation) 400 mg 5 times a day are prescribed. Treatment should be started as soon as possible after the onset of infection. To prevent recurrence of herpes simplex, patients with normal immune status are prescribed 200 mg 4 times a day every 6 hours or 400 mg twice a day every 12 hours. When relapsed, treatment is started in the prodromal period or with the appearance of the first elements of the rash. Therapy should be interrupted periodically after 6-12 months( to identify possible changes during the course of the disease).To prevent recurrence of herpes simplex, immunocompromised patients are prescribed 200 mg 4 times a day every 6 hours. In case of severe immunodeficiency( after bone marrow transplantation or intestinal absorption violation) -400 mg 5 times a day. The duration of the preventive course of therapy is determined by the length of the period when there is a risk of infection. Children from 2 years are prescribed the same doses as adults. For treatment of primary genital hermetic infection, 200 mg 5 times a day for 5 to 10 days, with relapse 200 mg 5 times a day for 5 days. For prophylaxis, 200 mg 4 times a day or 400 mg twice a day for 6 to 12 months;Against the background of severe immunodeficiency - 400 mg 4 times a day( treatment continues until there is a risk of risk).For the treatment of chickenpox and herpes zoster, 800 mg are administered orally 5 times a day every 4 hours, except during the night sleep. The course of treatment is 7 days. Children older than 6 years - 800 mg 4 times a day;2 - 6 years - 400 mg 4 times a day. A more accurate dose can be determined from the calculation of 20 mg / kg, but not more than 800 mg 4 times a day. The course of treatment is 5 days.

In patients with impaired renal function: in the treatment and prevention of infections caused by herpes simplex, in patients with Cl creatinine & lt;10 ml / min. Dosing should be reduced to 200 mg 2 times a day at 12-hour intervals;

in the treatment of infections caused by herpes zoster, in patients with Cl creatinine & lt;10 ml / min. It is recommended to reduce the dosage to 800 mg 2 times a day at 12-hour intervals, with Cl creatinine up to 25 ml / min. Is prescribed for 800 mg 3 times a day at 8-hour intervals.

patients immunocompromised( HIV / AIDS, or after bone marrow transplantation) due to application of the cream should be administered acyclovir systemic administration of the drug, as in the case of heavy flows and recurrent herpes infection. Long-term or repeated treatment with acyclovir patients with reduced immunity can lead to the appearance of strains of viruses that are insensitive to its action. The majority of isolated strains of viruses that are insensitive to acyclovir show a relative lack of viral thymidine kinase, strains with altered thymidine kinase or with altered DNA polymerase were isolated. In-vitro action of acyclovir on isolated strains of herpes simplex virus may cause the appearance of less sensitive strains.

The use of acyclovir during pregnancy is indicated in cases where the benefit to the mother exceeds the potential risk to the fetus.

In the course of therapy with high oral doses of the drug, it is necessary to ensure a sufficient supply of liquid to the patient's body.

During the treatment with acyclovir, breast-feeding should be discontinued.

In cases of impairment of the excretory function of the kidneys and the elderly, the dose is reduced in view of the clearance of creatinine.

In case of allergic reactions, the drug should be discontinued.

Side effects of Acyclovir Stud.

When the drug is applied, skin rashes, gastrointestinal disorders such as nausea, vomiting, abdominal pain, constipation and diarrhea, headache, fatigue, dizziness, hallucinations, hyperbilirubinemia may occur. All these symptoms disappear after discontinuation of therapy with acyclovir.

Who is contraindicated Acyclovir Stud?

  • Children under 2 years.
  • Hypersensitivity to the drug.

Interaction of Acyclovir Stud.

Probenecid reduces the excretion of acyclovir by 30%, which causes an increase in the half-life of acyclovir.

Overdose of Acyclovir Herd.

The maximum dose of acyclovir 5 g, taken at a time, does not cause intoxication or overdose. But patients who took a dose exceeding 5 g should be carefully examined for signs of intoxication.